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KMID : 0613820140240050491
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Journal of Life Science
2014 Volume.24 No. 5 p.491 ~ p.497
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Biological Activity of Extracts of the Starfish Asterias amurensis
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Go Hye-Jin
Jo Mi-Jeong
Kim Tae-Young
Hong Yong-Ki
Kim Kun-Do
Lee Byung-Woo
Park Nam-Gyu
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Abstract
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Nowadays, starfish is one of problems about interruption of marine ecosystem, so many researchers are focusing on application of the starfish (Asterias amurensis). In this study, we investigated the contractile and relaxant activity of the smooth muscles and the antimicrobial and antioxidant activity of six different tissues (muscle, gut, liver, tube feet, gonads, and body) of A. amurensis. Frozen samples were extracted with distilled water containing 1% acetic acid. Extracts from all the tissues, except the body tissue, showed potent antimicrobial activity against Escherichia coli D31. The dorsal retractor muscles (DRM) of muscle and gut extracts showed strong contraction responses. On the other hand, contractile activity on esophagus of squid Todarodes pacificus could be detected in all tissues tested. The contractile activity of the liver extract was higher than that of the other tissues. The body, tube feet, and liver extracts showed the contractile activity on the intestine of the panther puffer fish (Takifugu pardalis). Relaxation response on the DRM of starfish (A. pectinifera) was observed in all tissues tested. Increased antioxidant activity was observed in the gut, liver, and body extracts. The results suggest that the starfish (A. amurensis) is a potential source of novel bioactive compounds.
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KEYWORD
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Antimicrobial activity, antioxidant activity, contraction and relaxation, starfish Asterias amurensis
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